Additional file 1.

Summary of all miRNA datasets performed on popular platforms in GEO (represented by at least 25 arrays, data from July 2011). Paired datasets are marked in green with mRNA array platform and number of samples stated). Description and remarks: All the data have been derived from NCBI Gene Expression Omnibus (http://www.ncbi.nlm.nih.gov/geo/). The newest and most advanced, 3rd version of Agilent Human miRNA is represented only by 49 samples, gathered in 5 datasets. The older Agilent array (version 2.0, capable of measuring 723 microRNAs), listed currently as most popular global miRNA expression test in GEO is represented only by 17 datasets containing 539 samples. Among 10 major miRNA microarray platforms available in GEO (those platforms are represented by more than 25 arrays) only 23 experiments have been identified as paired miRNA-mRNA. The vast majority of those assays concern large cancer tissue expression studies, so the chance of finding a dataset on different biological subject is relatively low.

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Stempor et al. BMC Genomics 2012 13:620   doi:10.1186/1471-2164-13-620