Open Access Research article

Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment

A Eliot Shearer1,2†, Michael S Hildebrand1†, Harini Ravi3†, Swati Joshi3, Angelica C Guiffre3, Barbara Novak4, Scott Happe3, Emily M LeProust4 and Richard JH Smith1,2,5*

1 Department of Otolaryngology – Head & Neck Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA

2 Department of Molecular Physiology & Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA

3 Agilent Technologies, Cedar Creek, TX, USA

4 Agilent Technologies, Santa Clara, CA, USA

5 Interdepartmental PhD Program in Genetics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA

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BMC Genomics 2012, 13:618 doi:10.1186/1471-2164-13-618

Published: 14 November 2012

Additional files

Additional file 1:

Table S1. Positive Control Mutations.

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Additional file 2:

Table S2. 8 bp barcodes used.

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