Cross-species comparison of GC3 between orthologs. Two-dimensional plots of GC3 for orthologous gene pairs are shown for rat snake-chicken (A, B), rat snake-Chinese soft-shelled turtle (C), rat snake-human (D), chicken-human (E), Chinese soft-shelled turtle-human (F), rat snake-green anole lizard (G), chicken-Chinese soft-shelled turtle (H) and rat snake-Xenopus tropicalis (I). At (B), orthologs are divided into the following four categories as described in text: 1) genes located on macrochromosomes in both species (black dots), 2) genes on microchromosomes in both species (red dots), 3) genes on macrochromosomes in the snake and on microchromosomes in the chicken (green dots), and 4) genes on microchromosomes in the snake and on macrochromosomes in the chicken (blue dots, i.e., PGK1, ATRX and STAG2; see Figure 1).
Matsubara et al. BMC Genomics 2012 13:604 doi:10.1186/1471-2164-13-604