Table 3

Gene ontology (GO) terms enriched in LSRN and DE sets of genes expressed in LG/J and SM/J strain tibialis anterior muscle
GO-Terms enriched DE genes LSRN genes
Category Go-Term Go-Description Count % PValue Fold Enrichment Benjamini Count % PValue Fold Enrichment Benjamini
GOTERM_CC_FAT GO:0043292 contractile fiber 18 1.83 1.87E-06 4.01 9.10E-05 16 3.02 7.06E-08 5.88 6.99E-06
GOTERM_CC_FAT GO:0044449 contractile fiber part 17 1.73 2.20E-06 4.18 9.36E-05 15 2.84 1.31E-07 6.09 9.70E-06
GOTERM_CC_FAT GO:0030016 myofibril 18 1.83 9.98E-07 4.18 5.67E-05 16 3.02 3.89E-08 6.14 1.16E-05
GOTERM_CC_FAT GO:0044429 mitochondrial part 49 4.99 7.64E-06 1.98 2.61E-04 36 6.81 2.55E-06 2.40 1.51E-04
GOTERM_CC_FAT GO:0016460 myosin II complex 6 0.61 1.38E-04 10.58 3.36E-03 6 1.13 1.24E-05 17.46 6.13E-04
GOTERM_CC_FAT GO:0005759 mitochondrial matrix 21 2.14 8.33E-05 2.73 2.36E-03 17 3.21 1.70E-05 3.64 7.23E-04
GOTERM_CC_FAT GO:0031980 mitochondrial lumen 21 2.14 8.33E-05 2.73 2.36E-03 17 3.21 1.70E-05 3.64 7.23E-04
GOTERM_CC_FAT GO:0032982 myosin filament 6 0.61 4.65E-04 8.46 9.87E-03 6 1.13 4.37E-05 13.97 1.62E-03
GOTERM_CC_FAT GO:0016459 myosin complex 11 1.12 5.18E-04 3.82 1.03E-02 10 1.89 5.33E-05 5.73 1.76E-03
GOTERM_CC_FAT GO:0005859 muscle myosin complex 5 0.51 8.20E-04 10.58 1.26E-02 5 0.95 1.20E-04 17.46 2.73E-03
GOTERM_CC_FAT GO:0005739 mitochondrion 94 9.58 4.62E-05 1.50 1.43E-03 62 11.72 1.02E-04 1.64 2.75E-03
GOTERM_CC_FAT GO:0005740 mitochondrial envelope 34 3.47 8.90E-04 1.84 1.31E-02 24 4.54 8.65E-04 2.14 1.50E-02
GOTERM_MF_FAT GO:0017076 purine nucleotide binding 117 11.93 1.90E-04 1.38 4.57E-02 80 15.12 6.56E-05 1.54 1.85E-02
GOTERM_CC_FAT GO:0005863 striated muscle thick filament 4 0.41 4.90E-03 10.58 6.24E-02 4 0.76 1.16E-03 17.46 1.90E-02
GOTERM_CC_FAT GO:0044421 extracellular region part 65 6.63 6.92E-06 1.78 2.62E-04 38 7.18 1.42E-03 1.71 2.20E-02
GOTERM_CC_FAT GO:0005743 mitochondrial inner membrane 28 2.85 8.09E-04 2.00 1.31E-02 19 3.59 2.12E-03 2.24 2.96E-02
GOTERM_CC_FAT GO:0031966 mitochondrial membrane 31 3.16 2.53E-03 1.78 3.39E-02 22 4.16 2.04E-03 2.09 2.98E-02

Count – number of genes from the list involved in term; % - percentage of all genes in the list; PValue – modified Fisher Exact p-Value for enrichment; Benjamini – false discovery rate corrected P-values.

Lionikas et al.

Lionikas et al. BMC Genomics 2012 13:592   doi:10.1186/1471-2164-13-592

Open Data