Allele-specific PCF analysis of SNP array data. Results are shown for a breast carcinoma sample in the MicMa cohort for chromosome 1 (panel a) and chromosome 17 (panel b). The points in the upper two panels show observed total copy numbers (logR) while the points in the lower two panels show observed B allele frequencies (BAF). The red curves show the result of applying the allele-specific PCF segmentation method to the data. The plot was created with the function plotAllele in copynumber.
Nilsen et al. BMC Genomics 2012 13:591 doi:10.1186/1471-2164-13-591