Table 1

Characteristic phenotypes of HAB vs. LAB mice (F0 mice, N = 8 per gender and line); values are represented as mean ± standard error of means (SEM); corrected p-values refer to Bonferroni correction and are sorted by p-values of comparison in male mice
Phenotype HAB males mean±SEM LAB males mean±SEM p (males) corrected p (males) HAB females mean±SEM LAB females mean±SEM p (females) correctedp (females)
EPM - percent time on the open arm 4±1 74±2 0.0000 0.0000 6±1 61±6 0.0000 0.0011
EPM - percentage of open arm entries 17±2 63±4 0.0000 0.0000 20±3 53±6 0.0005 0.0115
TST - total immobility time [s] 113±10 4±1 0.0000 0.0002 112±11 7±3 0.0000 0.0010
EPM - closed arm entries 19±1 8±1 0.0000 0.0007 19±1 10±2 0.0020 0.0510
EPM - full open arm entries 0±0 13±2 0.0002 0.0049 0±0 9±1 0.0002 0.0060
EPM - open arm entries 4±1 13±2 0.0016 0.0461 5±1 11±2 0.0102 0.2555
TST - latency to 1st immobility [s] 101±5 232±28 0.0023 0.0633 105±12 235±40 0.0137 0.3423
PHYS - total fluid intake [ml] 6±1 11±1 0.0027 0.0746 NA NA NA NA
OF - total distance travelled [m] 9±2 24±4 0.0042 0.1180 14±2 29±2 0.0003 0.0078
PHYS - daily water intake [ml/g] 0.22±0.03 0.36±0.03 0.0044 0.1231 NA NA NA NA
PHYS - urine osmolality [osmol/kg] 2.9±0.2 2.3±0.2 0.0164 0.4595 NA NA NA NA
EPF - frequency of head dips 4±2 12±3 0.0313 0.8760 4±2 14±6 0.1914 1.0000
HPA-RT - increase in CORT [μg/l] 110±16 163±18 0.0360 1.0000 187±27 254±26 0.0995 1.0000
EPM - latency to 1st open arm entry [s] 87±24 27±5 0.0391 1.0000 118±30 52±12 0.0702 1.0000
EPF - latency to 1st head dip [s] 138±42 33±13 0.0420 1.0000 138±48 110±61 0.7244 1.0000
HPA-RT - stress CORT [μg/l] 118±13 165±15 0.0499 1.0000 207±23 260±20 0.1018 1.0000
EPF - total grooming time [s] 0.84±0.84 4.79±1.77 0.0765 1.0000 1±1 1.25±1.25 0.8789 1.0000
FST - total swimming time [s] 111±25 168±20 0.0994 1.0000 184±27 187±38 0.9448 1.0000
FST - total floating time [s] 165±24 118±21 0.1548 1.0000 128±28 119±34 0.8423 1.0000
OF - total time in the inner zone [s] 7±2 3±2 0.2047 1.0000 6±4 11±4 0.4170 1.0000
EPF - frequency of grooming 0.3±0.3 0.9±0.4 0.2297 1.0000 0.3±03 0.5±0.5 0.6674 1.0000
FST - latency to 1st floating [s] 110±7 95±10 0.2469 1.0000 96±5 121±16 0.1768 1.0000
HPA-RT - basal CORT [μg/l] 6.8±2.5 4.3±0.8 0.3724 1.0000 19±13 11±7 0.6019 1.0000
OF - entries to the inner zone 5.5±2.5 3.1±1.8 0.4510 1.0000 6.8±2.8 8.5±3.5 0.6991 1.0000
EPM - all arm entries 23±2 21±3 0.4732 1.0000 24±2 21±3 0.3112 1.0000
FST - total struggling time [s] 87±9 80±9 0.5799 1.0000 52±7 58±8 0.6015 1.0000
PHYS - body weight [g] 29±1 29±1 0.6776 1.0000 22±1 24±1 0.1141 1.0000
EPM - sum of total arm entries 23±2 21±3 0.4600 1.0000 24±2 21±3 0.5610 1.0000

Gonik et al.

Gonik et al. BMC Genomics 2012 13:579   doi:10.1186/1471-2164-13-579

Open Data