Distribution of P. gingivalis ATCC 33277 essential genes by Cluster of Orthologous Groups (COG) classifications.A) Number of genes within a COG category; essential genes in blue and entire genome in red. B) Percent of essential genes within a COG category from total number in genome; red line represents the 22% that 463/2102 of the percent essential over the entire genome. [A = RNA processing and modification, B = Chromatin structure and dynamics, C = Energy production and conversion, D = Cell cycle control, E = Amino acid metabolism and transport, F = Nucleotide metabolism and transport, G = Carbohydrate metabolism and transport, H = Coenzyme metabolism, I = Lipid metabolism, J = Translation, K = Transcription, L = Replication and repair, M = Cell wall/membrane/envelop biogenesis, N = Cell motility, O = Post-translational modification, protein turnover, chaperone functions, P = Inorganic ion transport and metabolism, Q = Secondary structure, T = Signal transduction, U = Intracellular trafficking and secretion, Y = Nuclear structure, Z = Cytoskeleton, R = General functional prediction only, S = Function unknown].
Klein et al. BMC Genomics 2012 13:578 doi:10.1186/1471-2164-13-578