Figure 6.

Effects of HBV core protein binding to host gene promoters. Relative luciferase activity was measured in cells co-transfected with one of six tumor pathogenesis-associated genes and the HBc gene. The pGL3-basic plasmid was used as the negative control. The vertical axis represents the relative proportion of luciferase activity of (cells co-transfected with HBc expression vector)/(cells transfected without HBc expression vector). Data are expressed as mean ± SD, *p < 0.05. Basic-P, pGL3-basic vectors; HRAS-P, NTRK2-P, PDGFA-P, IGF1R-P, SRC-P and P53-P represent the pGL3-basic-constructed plasmids for the promoters of HRAS, NTRK2, PDGFA, IGF1R, SRC and P53 genes, respectively

Guo et al. BMC Genomics 2012 13:563   doi:10.1186/1471-2164-13-563
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