Table 2

Summary of miR-181b correlation analyses for canonical and non-canonical miRNA-mRNA outcomes
Accuracy FPR FNR
miR Modulation
miR R2: 0.995; p<0.0001 R2: 1.000; p<0.0001 R2: 0.976; p<0.0001
anti-miR R2: 0.994; p<0.0001 R2: 1.000; p<0.0001 R2: 0.985; p<0.0001
Bidirectional R2: 1.000; p<0.0001 R2: 1.000; p<0.0001 R2: 0.970; p<0.0001
Cell Type
HEK-293 R2: 0.996, p<0.0001 R2: 1.000, p<0.0001 R2: 0.988, p<0.0001
HeLa R2: 0.996, p<0.0001 R2: 1.000, p<0.0001 R2: 0.983, p<0.0001
SH-SY5Y R2: 1.000, p<0.0001 R2: 1.000, p<0.0001 R2: 0.989, p<0.0001
Conservation
Conserved R2: 0.986, p<0.0001 R2: 0.751, p=0.0196 R2: 0.193, p=0.6183
Non-Conserved R2: 0.959, p<0.0001 R2: 0887, p=0.0014 R2: 0.835, p=0.0051
Seed Sequence
8mer R2: 0.981, p<0.0001 R2: 0.803, p=0.0091 R2: 0.803, p=0.0092
7mer-m8 R2: 0.970, p<0.0001 R2: 0.853, p=0.0034 R2: 0.790, p=0.0112
7mer-1A R2: 0.975, p<0.0001 R2: 0.780, p=0.0131 R2: 0.782, p=0.0127

Carroll et al.

Carroll et al. BMC Genomics 2012 13:561   doi:10.1186/1471-2164-13-561

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