Hierarchical clustering analysis of the log2value of differentially expressed miRNAs in myocardial infarction. Dual colour experiments and swap-dye were performed, using Cy3 and Cy5 to compare miRNAs expression in infarcted tissue and corresponding remote myocardium. Statistical analysis and hierarchical clustering was performed using Acuity 4.0 analytical software. The results are displayed in a heat map. The legend on the right indicates the miRNA shown in the corresponding row, all of which are human specific. The bar code on the bottom shows the colour scale of the log2 value. Each column represents data from one microarray. The heat map was constructed of 43 miRNAs dysregulated in all of the microarrays performed.
Boštjančič et al. BMC Genomics 2012 13:552 doi:10.1186/1471-2164-13-552