Canonical pathway significantly detected when contrasting the up (red) and (green) down-regulated genes in H compared to L group. X-axis values are the log(B-H correction p-value) and Y-axis values are the canonical pathways. The statistical significance of pathway modulation was calculated via a right-tailed Fisher’s Exact test in Ingenuity Pathway analysis and represented as –log (P value): -log values exceeding 1.30 were significant false discovery rate (FDR) <0.05).
Ramayo-Caldas et al. BMC Genomics 2012 13:547 doi:10.1186/1471-2164-13-547