Paired genes have a tighter transcriptional response following the release from alpha-factor arrest and progression through the cell-cycle. The transcriptional response of the unpaired RRB genes (n = 210) and RP genes (n = 154) following release from alpha-factor (A and B). Representative expression profiles for three adjacent paired RRB and RP genes during this stressor (C and D). The average PCC was determined by bootstrapping random pairings of genes from the RRB (E) and the RP genes (F). The actual average PCC for the unpaired genes is indicated by *, for the paired but not adjacent genes by ·, and the adjacent paired genes by #.
Arnone et al. BMC Genomics 2012 13:546 doi:10.1186/1471-2164-13-546