Additional file 4.

Most significant affected IPA canonical pathways. The most significant pathways are: MIF-mediated Glucocorticoid Regulation, MIF Regulation of Innate Immunity, NF-kB Signalling, IL-10 Signalling and Hypoxia Signalling in Cardiovascular System for T4 and Production of Nitric Oxide and Reactive Oxygen Species in Macrophages, LXR/RXR Activation, Toll-like Receptor Signalling, Acute Phase Response Signalling and MIF-mediated Glucocorticoid Regulation for T5.

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Cremonesi et al. BMC Genomics 2012 13:540   doi:10.1186/1471-2164-13-540