Open Access Highly Accessed Research article

GeneFriends: An online co-expression analysis tool to identify novel gene targets for aging and complex diseases

Sipko van Dam1, Rui Cordeiro1, Thomas Craig1, Jesse van Dam2, Shona H Wood1 and João Pedro de Magalhães1*

Author Affiliations

1 Integrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK

2 Laboratory of Systems and Synthetic Biology, Wageningen University, Wageningen, 6703 HB, Netherlands

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BMC Genomics 2012, 13:535  doi:10.1186/1471-2164-13-535

Published: 6 October 2012

Additional files

Additional file 1:

DAVID enrichment scores of 10 selected genes known to be related to cell cycle, immune response and fatty acid metabolism.

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Additional file 2:

Comparison of DAVID enrichment scores of 3 genes with known functions with CoXpressDB.

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Additional file 3:

Co-expressed genes with aging related gene seed list.

Format: TXT Size: 3.9MB Download file

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Additional file 4:

Co-expressed transcription factors with aging related gene seed list.

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Additional file 5:

Co-expressed genes with causative cancer gene seed list.

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Additional file 6:

Co-expressed genes with Bc055324 and 4930547N16Rik.

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Additional file 7:

Co-expressed genes with mitochondrial complex I disease related gene seed list.

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Additional file 8:

Top 5% co-expressed genes with poorly annotated genes.

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Additional file 9:

Seed list containing causative cancer genes and seed list containing aging related genes.

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Additional file 10:

Transfection protocol.

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Additional file 11:

List of DAVID genes of which grouping is solely inferred from expression pattern.

Format: XLS Size: 47KB Download file

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