Table 3

Regulation of key signaling pathways in guinea pig lungs infected with M. tuberculosis
Pathway Up Down
MAPK MRAS, MAPK7, RAC1, TGFB1, MAPKAPK5, MAPKAPK2, FGFR3, IL1B, PLA2G2A, RAC2, RAP1B, SOS2, MAPK8IP3, RRAS, HSPB1, CACNA1E, ARRB2, MAP2K2, FGF17, STK4, SRF, PAK2 MEF2C, CACNB2, CACNB4, TAOK3, CACNG4, DUSP9, FGFR4, PPP5C, FGFR2, FGFR1, RAP1A, CACNA1C, FOS, TNF, RPS6KA1, TGFB3, PPM1A, FGF19, ATF4, AKT3, CRKL, MAPK11, FGF8, MAPK1, FGF2, TP53, PPP3CB, MAPK8IP2, FGF12, FGF10, MAP3K4, PLA2G2C, PLA2G5, PRKACG, PRKACA, CHUK, PTPRR, RASA1, CACNA1S, BRAF, MAP2K6, MAP2K1, DUSP2, DUSP4, RASGRP2
Wnt RAC1, CUL1, CSNK2A2, PPP2R1A, RAC2, CSNK1A1, PPP2CA, RHOA, PSEN1 PRICKLE1, CSNK1E, LRP5, PLCB3, EP300, TBL1XR1, CTBP1, WNT3, CAMK2G, CAMK2A, CCND1, NKD2, SMAD4, SMAD2, PPP2R5D, TP53, PPP3CB, CSNK2A1, CTNNB1, PRKACG, PRKACA, CAMK2D, LEF1, WNT10A, FBXW11, BTRC, FZD9, FZD3, TCF7L2
Calcium VDAC1, ERBB2, ATP2A1, GNAQ, TNNC1, CACNA1E, P2RX2, ADCY4, SLC25A6 PLCB3, ADRA1B, PHKG2, CACNA1C, ADORA2A, CAMK2G, CAMK2A, GNAS, PLN, HTR6, NOS1, RYR1, VDAC2, PPP3CB, SLC8A1, CYSLTR1, P2RX1, CALM2, ATP2B4, ATP2A3, PRKACG, PRKACA, CAMK2D, LTB4R2, CACNA1S, ADRB2, PLCG1

Jain et al.

Jain et al. BMC Genomics 2012 13:520   doi:10.1186/1471-2164-13-520

Open Data