Comparison of transcriptional response of guinea pig, human, non-human primate and mouse to M. tuberculosis infection. The Venn diagrams depict the degree of overlap between up regulated genes of (A) Guinea pig, human and non-human primates and (B) Guinea pig, human and mouse. The analysis included comparison of the list of differentials obtained from our study with that obtained from various microarray data available in the public database for TB infection in case of; human [GEO Accession no. GSE20050], mouse [GEO Accession no. GSE15335] and non-human primate [GEO Accession no. GPL10183]. Down regulated genes did not show any considerable overlap across the species, hence not depicted in the figure.
Jain et al. BMC Genomics 2012 13:520 doi:10.1186/1471-2164-13-520