Pulmonary pathology in M. tuberculosis infected guinea pigs. The figure depicts (A) representative photograph showing gross pathology of lungs of M. tuberculosis infected guinea pigs at 10 weeks post-infection; (B) lower magnification photomicrograph of H&E stained, formalin fixed and paraffin embedded 5 μm section of lung tissue exhibiting multiple coalescing granulomas with central necrotic core and (C) photomicrograph (at 40X) of Van Gieson stained 5 μm lung section exhibiting extensive fibrosis as evident from thick bands of collagen (red color) around the granulomatous regions. Scale bar represents 1000 μm.
Jain et al. BMC Genomics 2012 13:520 doi:10.1186/1471-2164-13-520