Figure 1 .
Numbers of putative E3s mined from the mouse and human genomes and the homologous genes between the two species. Gene list of protein-coding genes was compiled from lists of genes that can be detected using the Affymetrix microarray technology. Sequences of these genes were downloaded from NCBI Refseq database and were scanned for RING/U-box/HECT domains using the HMMER software. Homologue identification was based on the annotation of NCBI HomoloGene database. (A) Number of homologues of all protein-coding genes in humans and mice. The number in the intersection is the number of homologues while the other two represent genes unique to the two species. (B) Number of homologues of putative E3 genes in humans and mice. (C) Numbers of different E3 genes in humans, mice and yeasts.
Hou et al. BMC Genomics 2012 13:495 doi:10.1186/1471-2164-13-495