Two different candidate replication origins are adjacent to one orc/cdc6 gene (Hla_3512 or Hwa_HQ2959A). A. The sequence features of the two putative origins. The orc/cdc6 genes are indicated with black-boxed arrows, and their start site is numbered 1. The adjacent origins (I and II) were mapped with small arrowheads and rectangles indicating the ORB elements and AT-rich regions, respectively. Origin II, in both cases, contains conserved ORB elements, which are highlighted in blue. B. Logo representations of the ORB elements in the four candidate replication origins. The ORB elements (boxed) are highly conserved in Origin II in both cases.
Wu et al. BMC Genomics 2012 13:478 doi:10.1186/1471-2164-13-478