Comparative display of structural variants of the two genomes. A: For the outer circle, the number of chromosomal rearrangements was assessed in bins of 5 Mb for both the genomic (transparent blue) and cell line DNA (transparent red). In the inner circle inter-chromosomal rearrangements are displayed. Because of the transparent colors, overlaps between the two genomes appear in purple. B: For comparison, a similar visualization is shown as a smaller inset, plotting chromosomal rearrangements of the genomic DNA (blue) and the genome of an unrelated individual (red). C: Genome ploidies for the genomic and cell line DNA are shown in the outer and inner circle, respectively. The curve is colored in orange in genome stretches with a ploidy of smaller than 1, the area under the curve is filled blue when ploidy exceeds 2. The axes are spaced in increments of 0.5.
Nickles et al. BMC Genomics 2012 13:477 doi:10.1186/1471-2164-13-477