Table 1

Functional annotation for most informative genes
BTC Description: betacellulin
Chromosomal region: chr4q13-q21
GO-BP: cell proliferation, positive regulation of cell proliferation
GO-MF: epidermal growth factor receptor binding, growth factor activity, growth factor activity
GO-CC: extracellular region, soluble fraction, plasma membrane, integral to membrane
Pathway: ErbB signalling, ERK signaling
CNFN Description: cornifelin
Chromosomal region: chr19q13.2
GO-BP: keratinization
GO-MF: NA
GO-CC: cornified envelope, cytoplasm
Pathway: NA
C20orf11 Description: Protein C20orf11 (two hybrid-associated protein 1 with RanBPM) (Twa1)
Chromosomal region: chr20q13.33
GO-BP: NA
GO-MF: protein binding
GO-CC: nucleus
Pathway: NA
BUB3 Description: budding uninhibited by benzimidazoles 3 homolog (yeast)
Chromosomal region: chr10q26
GO-BP: mitosis, cell proliferation, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO-MF: protein binding
GO-CC: kinetochore, nucleus, cytosol
Pathway: Cell cycle role of APC in cell cycle regulation
IL1F7 Description: interleukin 1 family, member 7 (zeta)
Chromosomal region: chr2q12-q14.1
GO-BP: immune response
GO-MF: cytokine activity, interleukin-1 receptor binding, interleukin-1 receptor antagonist activity
GO-CC: extracellular region
Pathway: Systemic lupus erythematosus signaling, role of cytokines in mediating communication between immune cells, graft-versus-host disease signaling, p38 MAPK signaling, atherosclerosis signaling

Ainali et al.

Ainali et al. BMC Genomics 2012 13:472   doi:10.1186/1471-2164-13-472

Open Data