Genes identified as most informative through RF classification of skin tissues in four molecular groups (NN, PN, PP01 and PP02). Gini Index (GI) was used as variable importance measure for estimating the discriminative power of relevant features (genes) and, consequently, their relevance to disease state. The five most important genes in determining disease classes were BTC, CNFN, C20orf11, BUB3 and IL1F7. Genes with related annotation are listed in Table 1.
Ainali et al. BMC Genomics 2012 13:472 doi:10.1186/1471-2164-13-472