Table 6

Predicted mRNA targets for unique miRNA candidates validated by RT-qPCR
Annotation gene targets
miR-15a ALB, BCLAF1, C1QA, C1QB, CD163**, CYP19A1, CYP26B1**, FKBP1A**, FOXP3, IFNGR1, IL10RA**, IL10RB, IL18R1, IL6R, IRAK1BP1, MAPK8, NFKB1, PAK2, PDCD4**, SFTPD, SMAD7**, SOCS5**, TAB3**, TNFAIP1**
miR-21 CYP19A1, IL10, IL12A**, IL1B**, IRAK1BP1, PDCD4**, SFTPA1, SMAD7**, SOCS5, TAB2, TAB3**, TNFAIP3, ZNF41
miR-126 IL21R, TOM1**
miR-142-5p BCLAF1, CYP26B1, FKBP1A**, IL21R, IL6ST, MCL1**, SMAD2, TNFAIP3, TNFAIP6
miR-143-3p ALB, FN1, IFNG, IL10RA, IL10RB, IL18R1, IL21R, IL6R, IL6ST, IRAK1BP1, KHSRP, MAPK8, PAK2, POSTN TAB2, TNFAIP1, ZEB2, ZNF41
miR-146a-5p
    BCLAF1
, CCBP2**, CCL5, FN1, FTH1, HLA-A, IL6,
    IRAK1**
, POSTN, SMG1, TAB2, TERF1, TNFAIP3, TNFAIP8, TRAF6**, ZEB2, ZNF41
miR-148a ALB, C8A, CYP26B1, HLA-A, IL6ST, IRAK1, SMAD2**, SMAD7, ZEB2
miR-155 BCLAF1, CCL5, CYP26B1**, FN1, FTH1, IFNG, IL12A, IL13**, IL18R1, IL6ST, ILF3, INPP5D**, IRAK1BP1, PAK2**, PDCD4, SMAD2**, SOCS5**, TAB2**, TERF1**, TNFAIP6, TNFAIP8, ZEB2
miR-223 BCLAF, C8A, CYP26B1, IL6ST**, IRAK1BP1, KHSRP, SMG1, SOCS5, TAB2**, TNFAIP8, ZEB2, ZNF41
miR-451 CFI, IL6, IL6R, PAK2, TNFSF15, TOM1
miR-664-5p A2M, CYP26B1, IFNG, IL18R1**, IL1A**, IL8, JUN, KHSRP, MAPK8, MCL1, NFKB1, SMG1**, TERF1, TNFAIP1**
miR-d5 No predictions found

Only widely conserved target sites included. ** indicate target predicted by two or more algorithms. Bold and underlined protein coding gene symbol indicate miRNA:mRNA interaction featured in StarBase which includes CLIP-Seq experimental validation.

Podolska et al.

Podolska et al. BMC Genomics 2012 13:459   doi:10.1186/1471-2164-13-459

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