Table 5

Top 15 genes interactively regulated by PML knockdown and TNFα treatment
Refseq Entrez Symbol Definition siC.T-siC.U siP.T-siP.U siP.U-siC.U siP.T-siC.T siP∗T
NM_002996.3 6376 CX3CL1 Chemokine (C-X3-C motif) ligand 1 8.88 88.86 0.14 1.40 10.00
NM_006398.2 10537 UBD Ubiquitin D 7.74 73.62 0.95 9.07 9.51
NM_000450.1 6401 SELE Selectin E (endothelial adhesion molecule 1) 33.57 293.72 0.78 6.83 8.75
NM_020311.1 57007 CMKOR1 Chemokine orphan receptor 1 1.30 9.84 0.26 1.99 7.56
NM_001007595.1 388125 NLF2 Nuclear localized factor 2 1.40 8.14 0.60 3.48 5.79
NM_152851.1 64231 MS4A6A Membrane-spanning 4-domains, subfamily A, member 6A, transcript variant 3 0.18 0.99 0.23 1.27 5.51
NM_006623.2 26227 PHGDH Phosphoglycerate dehydrogenase 0.19 0.98 0.51 2.61 5.17
NM_052941.2 115361 GBP4 Guanylate binding protein 4 2.82 14.26 0.26 1.31 5.05
NM_006332.3 10437 IFI30 Interferon, gamma-inducible protein 30 1.64 8.07 0.60 2.97 4.93
NM_000963.1 5743 PTGS2 Prostaglandin-endoperoxide synthase 2 6.42 29.70 0.32 1.48 4.63
NM_004915.3 9619 ABCG1 ATP-binding cassette, sub-family G, member 1 1.02 3.74 0.34 1.25 3.68
NM_001024465.1 6648 SOD2 Superoxide dismutase 2, mitochondrial, nuclear gene encoding mitochondrial protein 14.96 54.60 0.85 3.08 3.65
NM_003046.2 6542 SLC7A2 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 25.69 93.30 0.76 2.75 3.63
NM_002970.1 6303 SAT1 Spermidine/spermine N1-acetyltransferase 1 1.01 3.56 0.62 2.18 3.53
NM_003855.2 8809 IL18R1 Interleukin 18 receptor 1 2.23 7.74 0.63 2.18 3.46
NM_017413.3 8862 APLN Apelin 1.28 0.18 3.71 0.52 0.14
NM_001255.1 991 CDC20 CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.98 0.16 35.74 5.99 0.16
NM_199160.1 26468 LHX6 LIM homeobox 6 0.49 0.10 0.95 0.19 0.20
NM_001067.2 7153 TOP2A Topoisomerase II alpha 0.90 0.19 15.98 3.32 0.21
NM_005733.1 10112 KIF20A Kinesin family member 20A 0.99 0.22 8.03 1.76 0.22
NM_016242.2 51705 EMCN Endomucin 0.38 0.09 0.59 0.14 0.23
NM_004701.2 9133 CCNB2 Cyclin B2 1.04 0.25 10.86 2.53 0.24
NM_018136.2 259266 ASPM Asp (abnormal spindle)-like, microcephaly associated (Drosophila) 0.92 0.22 10.06 2.41 0.24
NM_181803.1 11065 UBE2C Ubiquitin-conjugating enzyme E2C 0.96 0.23 24.06 5.95 0.24
NM_003186.3 6876 TAGLN Transgelin 3.67 0.91 0.85 0.23 0.27
NM_015234.3 221395 GPR116 G protein-coupled receptor 116 1.04 0.29 1.07 0.30 0.28
NM_014750.3 9787 DLG7 discs, large homolog 7 (Drosophila) 1.00 0.30 6.53 1.96 0.30
NM_003981.2 9055 PRC1 Protein regulator of cytokinesis 1 0.99 0.29 9.94 2.92 0.30
NM_016359.2 51203 NUSAP1 Nucleolar and spindle associated protein 1 0.97 0.29 11.76 3.40 0.30
NM_018131.3 55165 CEP55 centrosomal protein 55kDa 1.00 0.31 9.62 2.91 0.30

Cheng and Kao

Cheng and Kao BMC Genomics 2012 13:453   doi:10.1186/1471-2164-13-453

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