Table 2

Identification of pilus biosynthesis, oligopeptide transport, glucuronate metabolism, and lactose metabolism genes
Function Locus tag (Protein) Annotation Closest homolog outsideFrancisella locus tag, protein, identity, E-value
Pilus biosynthesis1
Fphi_0006 (582 aa) Type IV pili secretin component (PilQ) Csal_0612, 668 aa, 36%, 7e-84
Fphi_0007 (196 aa) Type IV pili lipoprotein (PilP) Rmet_3269, 179 aa, 37%, 2e-05
Fphi_0008 (199 aa) Type IV pili glycosylation protein (PilO) Lferr_0885, 217 aa, 24%, 2e-04
Fphi_0009 (187 aa) Type IV pili associated protein (PilN) Lferr_0888, 197 aa, 26%, 5e-05
Fphi_0010 (334 aa) Type IV pili, pilus assembly protein None
Fphi_0117 (592 aa) Type IV pili ATPase (PilB/PulE) Shewmr4_0420, 569 aa, 48%, 4e-147
Fphi_0118 (410 aa) Type IV pili polytopic inner membrane protein (PilC/PulF) Tgr7_0786, 403 aa, 42%, 7e-85
Fphi_0157 (194 aa) Type IV pili, pilus assembly protein (FimT) Shal_1142, 171 aa, 30%, 6e-11
Fphi_0422 (152 aa) Type IV pili fiber building block protein (PilA/PilE) Noc_2540, 147 aa, 35%, 7e-15
Fphi_0423 (145 aa) Type IV pili, pilus assembly protein (PilA/PilE) CV_4209, 155 aa, 33%, 5e-12
Fphi_0424 (409 aa) Type IV pili, pilus assembly protein (PilA/PilE) NMB0018, 170 aa, 30%, 3e-09
Fphi_0449 (313 aa) Type IV pili, pilus assembly protein (PilA/PilE) CtCNB1_4760, 144 aa, 28%, 3e-05
Fphi_0522 (304 aa) Type IV pilus assembly protein PilW None
Fphi_0763 (149 aa) Type IV pili, pilus assembly protein Tola_2518, 128 aa, 36%, 2e-15
Fphi_0996 (342 aa) Twitching motility protein (PilT) SO_3351, 345 aa, 58%, 4e-106
Fphi_1136 (337 aa) Type IV pilus assembly protein (PilW) None
Fphi_1587 (282 aa) Type IV pili leader peptidase and methylase (PilD) Maqu_2683, 291 aa, 41%, 9e-55
Fphi_1689 (297 aa) Type IV pilus biogenesis/stability protein (PilW) Kkor_1840, 263 aa, 30%, 1e-09
Fphi_1748 (111 aa) Type IV pilin (PilA) Hsero_0660, 168 aa, 28%, 3e-06
Oligopeptide transport2
Fphi_1024 (558 aa) ABC-type oligopeptide transport system, periplasmic component (OppA) Rahaq_2640, 546 aa, 38%, 1e-90
Fphi_1025 (312 aa) Oligopeptide ABC transporter inner membrane protein (OppB) EAMY_1936, 306 aa, 47%, 3e-77
Fphi_1026 (286 aa) Oligopeptide transport system permease protein (OppC) VP2089, 300 aa, 53%, 2e-84
Fphi_1027 (219 aa) Oligopeptide transport system permease protein (OppD) CV_4326, 333 aa, 61%, 3e-137
Fphi_1029 (324 aa) Oligopeptide transport ATP-binding protein (OppF) NT05HA_1387, 332 aa, 58%, 5e-105
Glucuronate metabolism3
F7308_1388 (520 aa) Rhamnogalacturonide transporter (RhiT) KPK_1307, 502 aa, 44%, 2e-116
F7308_1389 (776 aa) Alpha-glucosidase BL00280, 802 aa, 50%, 0.0
F7308_1390 (490 aa) D-mannonate oxidoreductase (UxuB) CJA_0180, 492 aa, 42%, 3e-105
F7308_1391 (396 aa) Mannonate dehydratase (UxuA) PROSTU_04181, 396 aa, 59%, 5e-135
F7308_1392 (321 aa) 2-keto-3-deoxygluconate kinase (KdgK) Sde_1269, 296 aa, 43%, 9e-59
F7308_1393 (182 aa) KDPG Aldolase (KdgA) BC1003_2949, 213 aa, 37%, 4e-34
F7308_1394 (471 aa) Glucuronate isomerase (UxaC) Sde_1272, 471 aa, 51%, 3e-140
F7308_1395 (463 aa) D-xylose-proton symporter (XylT) CBUD_1731, 463 aa, 43%, 3e-91
F7308_1396 (325 aa) Inositol oxygenase 56727 Miox, 285 aa, 37%, 3e-47
Lactose metabolism4
Fphi_0309 (655 aa) Beta-galactosidase BMD_1886, 651 aa, 42%, 2e-159
Fphi_0310 (394 aa) Sugar transport protein ZP_07631419, 394 aa, 31%, 2e-44

1Homologs of these genes are also found in strains TX07-7308 and ATCC 25015.

2Homologs of these genes are also found in strain ATCC 25015, but absent in strain TX07-7308.

3Homologs of these genes are also found in strain ATCC 25015, but absent in strain ATCC 25017.

4Homologs of these genes are also found in strain ATCC 25015, but absent in strain TX07-7308.

Siddaramappa et al.

Siddaramappa et al. BMC Genomics 2012 13:422   doi:10.1186/1471-2164-13-422

Open Data