A Receiver-Operator Characteristic curve (ROC) of the optimized PWM (mono-nucleotide and di-nucleotide) compared with the program Match. The red and blue lines represent mono and di-nucleotide PWMs respectively. The filled and blank circles represent the optimized cutoff for mono and di-nucleotide PWMs. The empty triangle on the top right represents the Match minFN cutoff and the filled and the blank square represents the performance of Match minFP and minSUM cutoff.
Nandi and Ioshikhes BMC Genomics 2012 13:416 doi:10.1186/1471-2164-13-416