Open Access Highly Accessed Research article

Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel

Alan D Winter1*, William Weir1, Martin Hunt2, Matthew Berriman2, John S Gilleard3, Eileen Devaney1* and Collette Britton1*

1 Institute of Infection, Immunity and Inflammation; College of Medical, Veterinary and Life Sciences; University of Glasgow, Garscube Estate, Bearsden Road, Glasgow, G61 1QH, UK

2 Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK

3 Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada

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BMC Genomics 2012, 13:4 doi:10.1186/1471-2164-13-4

Published: 4 January 2012

Additional files

Additional file 1:

Supplemental Results, Methods, Figures and Tables. This file contains supplemental results, supplemental methods, four supplemental figures (Figures S1-S4), nine supplemental tables (Tables S1, S2, S3A-S3C, S4A-S4C, and S5), and supplemental references.

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Additional file 2:

miRNAs identified by deep sequencing. This file contains full details of the miRNAs identified by deep sequencing.

Format: XLS Size: 166KB Download file

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Additional file 3:

miRNAs predicted by homology. This file contains full details of the miRNAs predicted by homology.

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Additional file 4:

Evolutionary conservation of miRNAs. This file contains the analysis of the evolutionary conservation of the identified miRNAs.

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Additional file 5:

miRNAs associated with protein coding genes. This file describes miRNAs associated with protein coding genes.

Format: XLS Size: 41KB Download file

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Additional file 6:

miRNA clusters. This file describes miRNA found clustered in the genome.

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Additional file 7:

siRNAs. This file contains anti-sense sequences for all libraries which were identified as endo-siRNAs.

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Additional file 8:

piRNAs. This file contains sequences identified from the piRNA analysis.

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Open Data