Open Access Research article

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica

Radhika Das1, Nathan Anderson2, MaryEllen I Koran1, Jennifer R Weidman1, Tarjei S Mikkelsen2, Michael Kamal2, Susan K Murphy3, Kerstin Linblad-Toh24, John M Greally5 and Randy L Jirtle6*

Author Affiliations

1 Department of Radiation Oncology, Duke University Medical Center, Box 3433, Durham, NC, 27710, USA

2 Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA

3 Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, 27708, USA

4 Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, 75123, Sweden

5 Department of Medicine (Hematology) and Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA

6 McArdle Laboratory for Cancer Research, Department of Oncology University of Wisconsin-Madison, 1400 University Avenue, Madison,, WI 53706, USA

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BMC Genomics 2012, 13:394  doi:10.1186/1471-2164-13-394

Published: 16 August 2012

Additional files

Additional file 1:

Table S1. Primers and genomic coordinates for SNPs used to analyze imprint status in M. domestica. Table S2. (A) Forward primers used for methylation analysis. (B) Reverse primers used for methylation analysis. Table S3. Genomic coordinates of regions analyzed for methylation in M. domestica. Table S4. Primers used for IGF2R antisense detection. Table S5. Primers used for the analysis of histone modifications. Table S6. Relative enrichment of histone modifications at M. domestica imprinted loci.

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