Additional file 1Additional file 1.

Table S1. Mutations in coding regions detected by Roche NimbleGen Inc. This table includes the data provided by Roche NimbleGen Inc. (RN) for the whole genome sequence analysis of the evolved PB12 strain. Section A lists 26 (21+5) non-synonymous point mutations in structural genes that accordingly to RN changed the coding regions of these genes. In fact only in 21 of these genes detected also by Winter Genomics Inc (WG), the mutations occurred (Table 1A). Section B presents the list of the 12 genes included in a large deletion in this strain. This list also includes the genes deleted in the parental PB11 strain, for the construction of this derivative lacking PTS (Figure 2). The table also includes (Section C), the list of the 20 genes in which synonymous point mutations occurred accordingly to RN. Those 16 in common with WG are in bold letters.

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Aguilar et al. BMC Genomics 2012 13:385   doi:10.1186/1471-2164-13-385