Table 2

Associations between expression levels of key miRNA biogenesis genes and mean RE-score
CEU YRI Pooled
Bonferroni P Slope Bonferroni P Slope Bonferroni P Slope
DROSHA 9.42 × 10−03 -10.23 1.37 × 10−05 -22.12 5.19 × 10−06 -15.64
DGCR8 0.036 11.57 0.95 -0.46 0.37 6.23
XPO5 0.47 -3.03 1.38 × 10−04 -17.85 2.17 × 10−03 -10.74
RAN 0.27 0.49 0.14 -0.94 0.75 -0.12
DICER1 8.51 × 10−03 -13.77 1.97 × 10−09 -26.18 5.57 × 10−10 -21.72
TRBP 2.95 × 10−05 12.26 0.085 8.12 2.68 × 10−04 10.60
EIF2C2 0.022 -6.25 1.39 × 10−07 -9.07 1.88 × 10−08 -8.41

P-values and slopes from the linear regression of expression level of genes in the miRNA biogenesis pathway against mean RE-score, in the CEU, YRI and for both populations pooled.

Geeleher et al.

Geeleher et al. BMC Genomics 2012 13:383   doi:10.1186/1471-2164-13-383

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