Additional file 5.

KEGG pathways and GO (biological process) categories that were over-represented in the S. mansoni-infected ileum. KEGG pathways and GO (biological process) categories that were over-represented in the S. mansoni-infected ileum are represented with their MAPP Name (KEGG pathway name), Z score (z-score), AdjustedP (adjusted permutation p-value calculated using the Benjamini-Hochberg method)), gene symbols, AVG-logFC (average log2FC for each enriched term calculated based on associated differential genes) and AVG-adj.P. Val (average adjusted p-value for each enriched term calculated based on associated differential genes, GOID (Gene ontology ID), GO Name (name of GO category). Threshold criteria for over-representation: z-score > 2, at least three genes from the input list in the enriched category, an adjusted permutation p-value ≤ 0.35. Top-scoring functional category groups for KEGG pathway and GO categories are shown in colour as follows: Cytokine-cytokine receptor interaction pathway and immune, defense response category group. Intestinal immune network for IgA production pathway and immune response category group. Complement and coagulation cascades pathway and protein activation cascade category group. ECM-receptor interaction pathway and cell adhesion category group. Fc epsilon RI signaling pathway and acute inflammatory response category. (Note: Although immune response category is common to more than one category group, it is coloured only once).

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Avula et al. BMC Genomics 2012 13:377   doi:10.1186/1471-2164-13-377