Table 3 |
||||
| Histopathological observations/changes | ||||
| Organ | Changes | PP | MP | P-value* |
| Liver | No significant findings | 39.0% | 33.3% | 0.39 |
| Mild fatty change | 38.1% | 31.4% | 0.312 | |
| Mild to moderate fatty change | 8.6% | 7.6% | 0.801 | |
| Moderate fatty change | 8.6% | 8.6% | n.d. | |
| Moderate to severe fatty change | 0.0% | 1.9% | 0.156 | |
| Severe fatty change | 0.0% | 0.0% | n.d. | |
| Perivascular infiltration | 2.9% | 6.7% | 0.196 | |
| Peri biliar ducts infiltration | 3.8%a | 21.0% | <0.001 | |
| Necrotic foci w/infiltration | 1.0% | 0.0% | 0.317 | |
| Mild congestion | 0.0% | 1.0% | 0.317 | |
| Focal necrosis | 0.0% | 2.9% | 0.082 | |
| Mild sinusoidal dilatation | 0.0% | 1.0% | 0.317 | |
| Biliar ducts esclerosis | 0.0% | 2.9% | 0.082 | |
| Biliar ducts proliferation | 0.0% | 0.0% | n.d. | |
| Foci of inflammatory cells | 0.0% | 1.0% | 0.317 | |
| Heart (ventricle) | No significant findings | 99.0% | 98.1% | 0.562 |
| Severe infiltration and myodegeneration | 1.0% | 1.0% | n.d. | |
| Infiltration, no myodegeneration | 0.0% | 1.0% | 0.317 | |
| Presence of melanin granules | 0.0% | 0.0% | n.d. | |
| Mid-intestine and Pyloric caeca | No significant findings | 100% | 100% | n.d. |
| Distal intestine | No significant findings | 97.1% | 95.2% | 0.472 |
| Infiltration of submucosa and lamina propria, widened of lamina propria within folds (simple and complex), prominent goblet cells/low number of supranuclear vacuoles | 2.9% | 4.8% | 0.472 | |
Histopathological observations/changes. Values (in percentage) represent occurrence where n = 105. Significantly different when P < 0.05, different superscript letters indicate significant differences within each row-wise comparison.
Tacchi et al. BMC Genomics 2012 13:363 doi:10.1186/1471-2164-13-363
