Table 3

Persistent changes in gene expression induced by lead
Gene Symbol Gene Title Probe Set ID Entrez Gene ID Fold Increase P-value
MT1M metallothionein 1M 217546_at 4499 18 1.03E-22
MT1G metallothionein 1G 204745_x_at 4495 17.7 1.64E-27
MT1H metallothionein 1H 206461_x_at 4496 14.2 6.96E-28
MT1X metallothionein 1X 208581_x_at 4501 13.9 1.90E-26
204326_x_at 4501 13 1.66E-25
MT1E metallothionein 1E 212859_x_at 4493 10.9 4.23E-26
MT2A metallothionein 2A 212185_x_at 4502 10.6 2.93E-27
MT1P2 metallothionein 1 pseudogene 2 211456_x_at 645745 9.55 2.96E-27
MT1F metallothionein 1F 217165_x_at 4494 8.86 1.29E-24
213629_x_at 4494 6.6 2.47E-21
210524_x_at 4494 4.62 2.72E-19
MT1E///MT1H///MT1M///MT1P2 metallothionein 1E///metallothionein 1H///metallothionein 1M///metallothionein 1 pseudogene 2 216336_x_at 4493///4496///4499///645745 7.44 4.60E-23
EDNRB endothelin receptor type B 204273_at 1910 11 1.11E-17
206701_x_at 1910 6.6 8.42E-13
204271_s_at 1910 5.99 3.32E-13
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 212224_at 216 4.37 6.93E-06
KITLG KIT ligand 226534_at 4254 3.19 2.02E-09
TDO2 tryptophan 2,3-dioxygenase 205943_at 6999 3.14 0.004728
TMEM158 transmembrane protein 158 213338_at 25907 2.96 6.16E-15
FAM70A family with sequence similarity 70, member A 219895_at 55026 2.87 0.000112
PTGR1 prostaglandin reductase 1 231897_at 22949 2.86 3.65E-08
228824_s_at 22949 2.74 4.81E-07
ARRDC4 arrestin domain containing 4 225283_at 91947 2.8 7.31E-11
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha) 204151_x_at 1645 2.68 0.000934
216594_x_at 1645 2.28 3.79E-05
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid) 211653_x_at 1646 2.47 4.10E-05
209699_x_at 1646 2.28 5.27E-05
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 204058_at 4199 2.53 9.73E-07
204059_s_at 4199 2.3 9.20E-08
SLC7A11 solute carrier family 7, (cationic amino acid transporter, y + system) member 11 207528_s_at 23657 2.58 3.45E-07
209921_at 23657 2.42 7.46E-06
217678_at 23657 2.37 4.72E-05
ASPH aspartate beta-hydroxylase 210896_s_at 444 2.41 1.80E-11
209135_at 444 2.5 3.04E-10
224996_at 444 2.08 9.56E-08
225008_at 444 1.87 4.93E-08
205808_at 444 1.58 7.60E-05
242037_at 444 1.57 1.32E-06
ENSG00000204134 --- 238727_at --- 2.23 0.000495
SLC12A8 solute carrier family 12 (potassium/chloride transporters), member 8 219874_at 84561 2.17 1.85E-08
PIR pirin (iron-binding nuclear protein) 207469_s_at 8544 2.01 0.000561

Gillis et al.

Gillis et al. BMC Genomics 2012 13:344   doi:10.1186/1471-2164-13-344

Open Data