Heritability vs. predictive accuracy. Relationship of heritability (computed on the observed binary scale) or proportion of variance explained to the maximal upper limit on AUC. The numbers next to the curves represent the prevalence. The maximal AUCs are compared with those that would exist if the genetic risk distribution followed a beta distribution, which is consistent with previous reports [10,12,13].
Dreyfuss et al. BMC Genomics 2012 13:340 doi:10.1186/1471-2164-13-340