PROFILE clustering of 129 KEGG metabolites with fold changes between cancer and normal tissues. Ordering of the metabolites along the x-axis reflects the distance of metabolites in the network of enzymatic reactions. Significant metabolite changes in the TS that could be validated in the VS (green) and not significant or not validated metabolite changes (yellow).
Budczies et al. BMC Genomics 2012 13:334 doi:10.1186/1471-2164-13-334