Additional file 1.

Source bias removal demonstrated with RNA spike-in controls. 64 Affymetrix hybridization control probesets were analyzed with principal component analysis before and after the application of Distance Weighted Discrimination. Red, GD19-PND67 samples from the EPA dataset. Black, GD11.5-16.5 samples from the Otu et al. [13] dataset.

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Lee et al. BMC Genomics 2012 13:33   doi:10.1186/1471-2164-13-33