Table 2

Significantly differentially expressed genes in acute phase response
Gene name Accession number Description RPKM-C RPKM-V Fold-change p-value
ahsg ENSDARG00000069293 Alpha-2-HS-glycoprotein 554.80 55.81 −11.84 7.26E-50
apoa4 ENSDARG00000040298 Apolipoprotein A-IV 266.33 164.60 −2.09 2.21E-04
tfrc ENSDARG00000012552 Transferrin receptor (p90, CD71) 23.29 13.29 −2.27 1.18E-04
c1qb ENSDARG00000044612 Complement component 1, q subcomponent 6.06 3.14 −2.23 6.06E-03
plg ENSDARG00000023111 Plasminogen 64.66 37.99 −2.18 6.73 E-04
aerping1 ENSDARG00000058053 C1 inhibitor 15.69 6.71 −2.93 5.49E-05
c2 ENSDARG00000019772 Complement component 2 24.57 52.88 2.06 2.99E-10
si:dkey-8 k3.2 ENSDARG00000038424 Complement C4 323.79 978.12 2.07 8.93E-13
cfb ENSDARG00000055278 Complement factor B 727.97 1914.46 2.09 3.38 E-03
apcs ENSDARG00000045089 Serum amyloid P component 309.74 872.88 2.16 1.64 E-04
cp ENSDARG00000010312 Ceruloplasmin (Fragment) 633.50 1737.21 2.19 2.74 E-03
c9 ENSDARG00000016319 Complement component C9 18.78 48.27 2.28 4.90E-157
cfhl2 ENSDARG00000056778 Complement factor H, like 2 11.76 38.65 2.28 6.44E-07
tfr2 ENSDARG00000089980 Transferrin receptor 2 10.84 34.09 2.51 2.58 E-04
fga ENSDARG00000020741 Fibrinogen alpha chain 375.41 1118.34 2.55 4.87E-05
c3a ENSDARG00000012694 Complement component c3a 1305.16 4584.02 2.77 1.21 E-03
serpina7 ENSDARG00000087143 Antitrypsin 466.41 1720.58 3.05 1.18E-05
c3 ENSDARG00000043719 PREDICTED: complement C3-H2-like 154.97 692.50 3.44 1.19E-08
serpine1 ENSDARG00000056795 Plasminogen activator inhibitor type 1 13.14 68.84 4.38 6.20E-14
cebpb ENSDARG00000042725 CCAAT/enhancer binding protein, beta 37.33 202.58 4.42 4.58E-13
fgg ENSDARG00000037281 Fibrinogen, gamma polypeptide 154.90 965.71 5.39 6.08E-15
fth1a ENSDARG00000015551 Ferritin 180.30 1233.87 5.45 9.51E-14
f2r ENSDARG00000060012 Coagulation factor II (Thrombin) receptor 0.38 3.11 6.57 6.63E-05
si:ch211-234p6.7 ENSDARG00000071456 C-reactive protein 0.37 3.41 9.71 2.46 E-04
atp7a ENSDARG00000003699 ATPase, Cu++ transporting 0.21 3.99 13.09 2.38E-06
hpx ENSDARG00000051912 Hemopexin 192.84 7565.38 31.36 3.57E-17
tlr5b ENSDARG00000052322 Toll-like receptor 5 2.17 98.99 36.41 7.93E-62
lygl1 ENSDARG00000056874 Lysozyme 11.85 641.71 41.37 1.70E-41
c7 ENSDARG00000057121 Complement component 7 6.38 435.85 63.02 4.13E-36
itln3 ENSDARG00000003523 Intelectin 3 52.98 8467.17 129.02 3.93E-33
lect2l ENSDARG00000033227 Leukocyte cell-derived chemotaxin 2 8.75 2597.52 222.85 8.92E-56
hp ENSDARG00000051890 Haptoglobin 14.36 7332.05 387.28 1.97E-30
saa ENSDARG00000045999 Serum amyloid protein A 1.24 1248.94 883.07 2.56E-66

Identification of all differentially expressed genes was based on p < 0.05. A p-value < 0.05 indicated that the gene was significantly altered in WED immunized fish with respect to mock-immunized fish. The absolute value of “Fold-change” is the magnitude of up- or down-regulation for each gene/homolog after WED immunization. Fold-change > 2 indicates up-regulation, and < −2 indicates down-regulation.

Yang et al.

Yang et al. BMC Genomics 2012 13:319   doi:10.1186/1471-2164-13-319

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