Evolutionary features of cystatins in arthropods. (A) Number of cystatin domains in each species distributed in base of their protein architecture. In brackets the number of repeats in multicystatin domains. CPI, single cystatin domain; MultiCPI, multicystatin domains. (B) Phylogenetic tree using the selected cystatin sequences from the different arthropod species. Coloured triangles show species-specific gene proliferations. In brackets the number of proteins in each subtree.
Santamaría et al. BMC Genomics 2012 13:307 doi:10.1186/1471-2164-13-307