Additional file 3.

Figure S3. List of Opisthokonta specific proteins identified by the 4 way comparative genomic analysis. Among the 320 proteins specific to H. sapiens and S. cerevisiae that were found by comparative genomic analysis, 245 proteins were confirmed and kept for further GO Term Enrichment analysis and 75 proteins were rejected. To identify the biological processes in which these 245 confirmed proteins were involved, we used the S. cerevisiae Gene Ontology (GO) annotation database and we also manually searched the SGD (Saccharomyces Genome Database) database. We highlighted the proteins involved in membrane trafficking (in red), in cytokinesis (in yellow), in metabolism (in chartreuse green), in trafficking and cytokinesis (in orange), in trafficking and metabolism (in khaki green), in metabolism and cytokinesis (in light green) and in the three processes in black. The proteins that did not belong to any of these catagories were highlighted in grey for the proteins involved in other biological processes and not highlighted proteins are of unknown function.

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De Craene et al. BMC Genomics 2012 13:297   doi:10.1186/1471-2164-13-297