Open Access Highly Accessed Research article

Transcriptome analysis of the honey bee fungal pathogen, Ascosphaera apis: implications for host pathogenesis

R Scott Cornman1, Anna K Bennett3, K Daniel Murray1, Jay D Evans2, Christine G Elsik3 and Kate Aronstein1*

Author Affiliations

1 Honey Bee Research Unit, USDA-ARS, Weslaco, TX, 78596, USA

2 Honey Bee Research Laboratory, USDA-ARS, Beltsville, MD, 20705, USA

3 Department of Biology, Georgetown University, Washington, DC, 20057, USA

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BMC Genomics 2012, 13:285  doi:10.1186/1471-2164-13-285

Published: 29 June 2012

Additional files

Additional file 1:

Table S1. (Supplemental).A. apismanual gene annotation according to functional groups. Showing gene names, database (GenBank or Bee Pests and Pathogens/AAPI) accession numbers and names of species with the highest similarity. If sequences were not found in either of the two databases, they were referenced by the isotig or contig trace numbers. Datasets referenced in this table are available as follows: Baylor College of Medicine Genome Project 17285, Ascosphaera apis USDA-ARSEF 7405 and Bee Pests and Pathogens (http://hymenopteragenome.org/beebase/?q=bee_pathogens webcite).

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Additional file 2:

Table S2. (Supplemental). Genes that are strong candidates for differential expression between axenic culture and host infection. Genes listed have both a length-normalized expression differential greater than two standard deviations from the local mean (see text) and a significant result of Fisher’s Exact Test for equal abundance of reads (with Benjamini-Hochberg correction for multiple tests).

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