Additional file 16.

Non-clonal read frequency in relation to the number of library amplification cycles. Each bar represents one MeDIP-seq lane. Letters after tissue labels designate biological replicates within tissue types. A. Clonal read frequency. B. Illumina sequencing library PCR amplification cycles. Asterisks indicate libraries for which 18-cycle and 21-cycle amplification products were mixed.

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Vining et al. BMC Genomics 2012 13:27   doi:10.1186/1471-2164-13-27