Degradation of maximal discrimination by increasing contamination of a genome with foreign DNA. The genome of Syn was contaminated with genes from either Pmm (solid symbols) or Tel (hollow symbols), measuring maximal discrimination either by W8 (□,■), codon bias (◊,♦), or GC% (∆,▲). Maximal discrimination measured by CGS is not shown because its reference set (hence its calculated scores) is not affected by contaminating foreign genes.
Elhai et al. BMC Genomics 2012 13:245 doi:10.1186/1471-2164-13-245