Performance for predicting relatedness based on CNP profiles generated by different methods. Each plot shows the Receiver Operator Characteristic (ROC) curve for predicting relatedness between individuals based on the similarity of their CNV profiles generated by different methods (CNV detection algorithms are indicated above each plot and merging procedures by colors). The analysis employed 162 pairs of individuals known to be related and 2000 pairs of unrelated individuals. Curves were made with the mean (solid lines) +/- one standard deviation (light blue or light red surfaces) from 100 permutations. The Precision-Recall Area Under the Curve (AUC) values are shown in the legends.
Valsesia et al. BMC Genomics 2012 13:241 doi:10.1186/1471-2164-13-241