Figure 2.

Overlap between CNVs identified from CoLaus and published CNVs. A) Counts of CNVs with different methods (see legend) are segregated according to their overlap with CNVs published in the Database of Genomic Variants. Overlap is measured by the Jaccard coefficient, i.e. the ratio between the intersection and the union of two groups of CNVs. Expected counts from (1000 times) reshuffled data are shown in gray (extending over one standard deviation). Estimated p-values are indicated for significant enrichment (red) or depletion (blue), with respect to these controls. Non significant p-values (α > 1%) are shown in black. B) Percentage of changes between observed and expected counts from A. Error bars indicate +/- one standard deviation.