Email updates

Keep up to date with the latest news and content from BMC Genomics and BioMed Central.

Open Access Highly Accessed Methodology article

Exome sequencing generates high quality data in non-target regions

Yan Guo1, Jirong Long2, Jing He3, Chung-I Li1, Qiuyin Cai2, Xiao-Ou Shu2, Wei Zheng2 and Chun Li34*

Author Affiliations

1 Center for Quantitative Sciences, Vanderbilt Ingram Cancer Center, Nashville, TN, USA

2 Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, TN, USA

3 Department of Biostatistics, Vanderbilt University, Nashville, TN, USA

4 Center for Human Genetics Research, Vanderbilt University, Nashville, TN, USA

For all author emails, please log on.

BMC Genomics 2012, 13:194  doi:10.1186/1471-2164-13-194

Published: 20 May 2012

Additional files

Additional file 1:

Table S1. Alignment Summary Table (read in millions). Table S2. Agilent SureSelect v1 (N=22, MAPQ>20). Table S3. SNP information for 22 SureSelect samples. Table S4. SNP information for 22 SureSelect samples (only considering dbSNP overlap). Table S5. SNP information for 6 1000 Genome Project samples. Table S6. SNP information for 6 1000 Genome Project samples (only considering dbSNP overlap). Table S7. SNP information for 6 TrueSeq samples. Table S8. SNP information for 6 TruSeq samples (only considering dbSNP overlap). Table S9. Positions with unbalanced read distribution in SureSelect data. Table S10. Blast Results for top 10 high depth Outside > 200bp regions in Agilent SureSelect Regions.

Format: XLSX Size: 1.9MB Download file

Open Data