Intensity of DNA curvature-related periodic signal in prokaryotic chromosomes and bacteriophages and comparison with random sequences. Top: The MaxQ* index (see Methods) is used as a measure of the intensity of DNA curvature-related periodicity in the analyzed sequence. Each chromosome or phage is represented by a point with the horizontal coordinate determined by the MaxQ* value and the vertical coordinate by the sequence length in bp. Primary chromosomes (the largest chromosome of a genome) are shown as red circles, secondary chromosomes as green triangles, and phages as blue crosses. Bottom: An analogous plot for randomized sequences. A random sequence was generated for each chromosome (red circles) and phage (blue crosses) reproducing the length and G + C content of the original sequence. The random sequences were subsequently processed in the same way as the original sequences in the top panel. The Genome Randomizer software was used to generate the random sequences (http://www.cmbl.uga.edu/downloads/programs/Genome_Randomizer/ webcite, ).
Abel and Mrázek BMC Genomics 2012 13:188 doi:10.1186/1471-2164-13-188