Figure 10.

Hook-hybridization characteristics of the arrays of the ratQC data set. (a) The width of the hook curves β increases with progressive degradation indicating the decrease of the non-specific background due to the loss of material (see Eq. (18)). Log d is the mean degradation index (Eq. (2)) and K the slope of the regression line. The mean level of specific hybridization changes only weakly with degradation (b). The fraction of absent probes is virtually unaffected by degradation (c). All parameters are estimated using the hook method [33,34]

Fasold and Binder BMC Genomics 2012 13:186   doi:10.1186/1471-2164-13-186
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