Table 1

Five largest up- and down-regulated miRNAs
miRNA probe Fold change Probable genesa predicted by both algorithms
miR-32*b 2.9
miR-466c-5p 2.8 22
miR-466d-5p 2.8 30
miR-466c 2.6 4
miR-466b 2.6 7
miR-466f-3pc 2.4 38
miR-375 −1.7 13
miR-378 −1.6 18
miR-347 −1.6 23
miR-15b −1.6 21
miR-154 −1.5 16

a Probable gene targets are candidates from a parallel mRNA expression array differentially expressed with cyclic stretch of 25% ΔSA at 6 hours, and predicted by both MicroCosm and TargetScan algorithms; see text for details.

b The majority of miRNAs with the “*” designation are considered passenger transcripts of a precursor miRNA, and do not have calculated TargetScan targets.

c MiR-466f-3p is the 7th highest up-regulated miRNA, and was chosen for subsequent validation studies; it is included here for reference.

Yehya et al.

Yehya et al. BMC Genomics 2012 13:154   doi:10.1186/1471-2164-13-154

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