“Promiscuous” miRNAs with multiple predicted mRNA targets. The 34 up-regulated (top) and 8 down-regulated (bottom) miRNAs were matched with predicted high probability mRNA targets from a parallel mRNA expression array using TargetScan and MicroCosm. Most miRNAs had multiple predicted gene targets. Of the 34 up-regulated miRNAs, 8 had >25 predicted targets each; of the 8 down-regulated miRNAs, only 3 had >20 predicted targets.
Yehya et al. BMC Genomics 2012 13:154 doi:10.1186/1471-2164-13-154