Table 5

Main pathways identified by profile-3 genes

Ingenuity Canonical Pathways

gene hits

-log(p-value)

Role of CHK Proteins in Cell Cycle Checkpoint Control

10

4.98

ATM

10

3.17

Cell Cycle: G1/S Checkpoint Regulation

9

2.40

Cell Cycle: G2/M DNA Damage Checkpoint Regulation

7

2.15

Aryl Hydrocarbon Receptor Signaling

15

2.02

RAN

4

1.91

LPS/IL-1 Mediated Inhibition of RXR Function

19

1.86

Nucleotide Excision Repair Pathway

6

1.81

Fructose and Mannose Metabolism

9

1.34

Li et al. BMC Genomics 2012 13:153   doi:10.1186/1471-2164-13-153